A well thought out villain can take an alright game and turn it into a great game. When it comes to games, villains are just as, if not more, important than the hero.
Handsome Jack is the main antagonist of Borderlands 2. He is ruthless, intelligent, egotistical and a little bit charming in a way. In fact, when it comes to egomaniacal bravado, Handsome Jack is unmatched. He pretty much has a little bit of everything you could want in a villain.
She may look like just a random brain in a jar, but that brain in a jar has the power to control hordes and hordes of space pirates. What's more, she has the ability to morph into a bipedal monstrosity that shoots lasers from it's eyes! Freaking lasers!
The Joker is one of the best comic book villains of all time and when Rocksteady brought him over to the video game world, he immediately became one of the best villains in video games as well. Joker's unpredictability and insanity perfectly hides his overwhelming intelligence. It's this that makes him such a great and terrifying antagonist.
Senator Steven Armstrong
For a game as over the top as Metal Gear Rising: Revengeance, it's only natural for it's final boss to be just as over the top, if not more, than the game itself. Senator Steven Armstrong is basically the personification of America. He is as American as Chuck Norris, eating a hot dog while flying on a bald eagle with red, white and blue feathers on the fourth of July. His motives make absolutely zero sense, but then again neither does the rest of the game.
It's hard to come by a character that's more deranged and unstable than Scott Shelby, a.k.a the Origami Killer. A tragic event in Scott's childhood where his father failed to save his brother from drowning, slowly shapes Scott over the years. Sadly unable to move on, he becomes a delusional murderer whom kidnaps children and gives their fathers a chance to save them, much like his father with his brother.
If you ever played against Psycho Mantis, you'll agree that he is probably one of the most memorable villains in video games. Other than his appearance, what makes him so memorable is his optic camouflage, psychic powers and ability to break the fourth wall by reading your thoughts.
One word that describes Dormin very well is puppeteer. Through the guise of a benevolent god who promises to revive Wander's fallen partner, Dormin tricks Wander into killing the 16 colossi sealing his power. Not only does he trick Wander, he also takes his body for a test drive.
Shodan is the OG of evil video game A.I. Her hatred toward humans could not be measured by computer chips and wires. What's more is that you created her, she is ever-present throughout the entire ship, she created parasitic entities that killed your crewmates by conducting experiments on you and she's trying to kill you.
It's fair to call him xenophobic, but the Illusive Man was neither good or evil. Pulling the strings from the background, the Illusive Man wanted to make sure humanity would remain amongst the top races in the galaxy. However, after the reapers were able to get into his brain, he lost control and became full blown evil, unknowingly geared toward the destruction of every single living race.
Did you know that the CSI Miami guy is based of Albert Wesker? Actually, that's not true, but it seems like it could be doesn't it? Known for his super strength, damaged psyche, and amazing sunglasses, Welker is one tough son of a gun that took couldn't be stopped. That is, until he got pumped full of bullets, hit with two rockets, and blasted by a volcano.
Calling Vaas Montenegro a colorful character is an understatement. In fact, he may have been the best character in video games in 2012. His character is almost Joker-esque in his ability to quickly shift from one extreme personality to another. For instance, one moment he'll be playfully conversing, even trying to relate with the main protagonist, a second later he becomes a cold-blooded murderer.
Andrew Ryan is the visionary behind Rapture. With his genius he was able to do the seemingly impossible, build a metropolis under water. Although his metropolis failed, you can't blame him for wanting your respect. What you can blame him for though is the thousands of lives he destroyed with his experiment. Ryan's hubris proved to be his downfall, but he still managed to become one of the best villains to date.
The guy has alien cells fused within his body and he summoned a meteor to take out the planet. We know you're the result of a crazy science experiment and you're super powerful, but c'mon man. Haven't you heard the saying with great power comes great responsibility?
This spiky shelled, flame-throwing turtle is obsessed with kidnapping princesses and wreaking havoc on the Mushroom Kingdom. However, if it wasn't for him the Mushroom Kingdom would be one boring place and the only place Mario could get some action would be under a sink.
She's the sociopathic super computer everyone loves, GLaDOS. Her passive aggressive, and occasionally murderous taunts is what makes her stand out the most. Also, unlike many other egotistical villains, GLaDOS knows when she's beat and it's time to throw in the towel.
Probably the best villain in any Final Fantasy game, Kefka has just the right balance of insanity, rage and terror. His insatiable thirst for power led him to poison a town's water supply killing hundreds in the process, destroy the world, then torturing the would be survivors. He is easily the most sadistic villain to ever be a part of the Final Fantasy series.